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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPE
All Species:
9.09
Human Site:
T2591
Identified Species:
16.67
UniProt:
Q02224
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02224
NP_001804.2
2701
316415
T2591
V
K
T
W
K
E
R
T
L
K
R
E
A
H
K
Chimpanzee
Pan troglodytes
XP_001170168
2701
316707
T2591
V
K
T
W
K
E
R
T
L
K
R
E
A
H
K
Rhesus Macaque
Macaca mulatta
XP_001110512
2701
316828
T2591
V
K
T
W
K
E
R
T
L
K
R
E
A
Y
K
Dog
Lupus familis
XP_852631
1216
141588
N1107
E
E
K
L
K
E
K
N
Q
Q
L
Q
E
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6RT24
2474
286506
E2364
N
E
V
K
T
W
E
E
R
T
L
K
R
D
S
Rat
Rattus norvegicus
Q7TSP2
1385
159522
L1276
L
E
E
V
Q
S
A
L
D
S
K
E
K
F
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420670
2150
248600
L2041
E
L
Q
L
K
E
E
L
R
K
W
K
E
R
A
Frog
Xenopus laevis
NP_001080954
2954
339950
Q2817
N
R
S
E
I
Y
S
Q
L
V
M
S
P
G
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524993
2013
231091
E1904
L
E
D
K
R
N
L
E
E
K
L
C
S
A
N
Honey Bee
Apis mellifera
XP_001121311
1418
164919
A1309
K
L
R
D
Q
V
D
A
L
R
M
R
L
Q
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781622
2537
290578
N2407
E
K
N
R
E
Y
R
N
E
L
R
R
E
H
Q
Poplar Tree
Populus trichocarpa
XP_002308893
1247
142380
K1138
G
K
V
N
T
L
E
K
E
M
I
I
L
S
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187629
1348
152938
E1239
A
S
S
R
T
I
D
E
P
R
N
S
L
E
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
37.8
N.A.
60.5
21.2
N.A.
N.A.
37.1
31
N.A.
N.A.
26.1
24.8
N.A.
25.5
Protein Similarity:
100
99.2
98
42
N.A.
75
35.7
N.A.
N.A.
55
52.2
N.A.
N.A.
45.6
37.8
N.A.
48.8
P-Site Identity:
100
100
93.3
13.3
N.A.
0
6.6
N.A.
N.A.
20
13.3
N.A.
N.A.
6.6
6.6
N.A.
26.6
P-Site Similarity:
100
100
100
46.6
N.A.
13.3
33.3
N.A.
N.A.
26.6
26.6
N.A.
N.A.
33.3
20
N.A.
40
Percent
Protein Identity:
23.9
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
34.6
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
8
0
0
0
0
24
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% C
% Asp:
0
0
8
8
0
0
16
0
8
0
0
0
0
8
0
% D
% Glu:
24
31
8
8
8
39
24
24
24
0
0
31
24
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
8
8
0
0
0
% I
% Lys:
8
39
8
16
39
0
8
8
0
39
8
16
8
8
39
% K
% Leu:
16
16
0
16
0
8
8
16
39
8
24
0
24
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
16
0
0
0
8
% M
% Asn:
16
0
8
8
0
8
0
16
0
0
8
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% P
% Gln:
0
0
8
0
16
0
0
8
8
8
0
8
0
8
16
% Q
% Arg:
0
8
8
16
8
0
31
0
16
16
31
16
8
8
0
% R
% Ser:
0
8
16
0
0
8
8
0
0
8
0
16
8
8
16
% S
% Thr:
0
0
24
0
24
0
0
24
0
8
0
0
0
0
0
% T
% Val:
24
0
16
8
0
8
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
24
0
8
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
16
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _